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GABA Transporter 3 Rabbit pAb (bs-13260R)  
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50ul/1180.00元
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產(chǎn)品編號 bs-13260R
英文名稱 GABA Transporter 3 Rabbit pAb
中文名稱 γ氨基丁酸運載蛋白3抗體
別    名 GABT3; GAT-3; GAT3; S6A11_HUMAN; Slc6a11; Sodium-and chloride-dependent GABA transporter 3; SOLUTE CARRIER FAMILY 6(NEUROTRANSMITTER TRANSPORTER, GABA), MEMBER 11; Solute carrier family 6 member 11.  
研究領(lǐng)域 細胞生物  神經(jīng)生物學(xué)  轉(zhuǎn)運蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human (predicted: Mouse,Rat)
產(chǎn)品應(yīng)用 WB=1:500-2000,Flow-Cyt=1ug/test
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 71 kDa
檢測分子量
細胞定位 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human GABA Transporter 3/GAT 3: 531-632/632 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 Gamma-aminobutyric acid (GABA) is a major inhibitory neurotransmitter. GABAergic neurotransmission is terminated by the uptake of GABA into the presynaptic terminal and the surrounding astroglial cells by sodium-dependent transporters, such as SLC6A11 (Borden et al., 1994 [PubMed 7874447]).[supplied by OMIM, Nov 2010]

Function:
Terminates the action of GABA by its high affinity sodium-dependent reuptake into presynaptic terminals.

Subcellular Location:
Membrane; Multi-pass membrane protein.

Tissue Specificity:
Widespread distribution in the brain.

Similarity:
Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A11 subfamily.

SWISS:
P48066

Gene ID:
6538

Database links:

Entrez Gene: 6538 Human

Omim: 607952 Human

SwissProt: P48066 Human

Unigene: 657405 Human



產(chǎn)品圖片
Sample:A431 (human)cell Lysate at 40 ug Primary: Anti-GABA Transporter 3 (bs-13260R)at 1/300 dilution Secondary: IRDye800CW Goat Anti-RabbitIgG at 1/20000 dilution Predicted band size: 71 kD Observed band size: 71 kD
Blank control: HepG2. Primary Antibody (green line): Rabbit Anti-GABA Transporter 3 antibody (bs-13260R) Dilution: 1μg /10^6 cells; Isotype Control Antibody (orange line): Rabbit IgG . Secondary Antibody : Goat anti-rabbit IgG-PE Dilution: 1μg /test
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